Speaker
Description
²¹²Pb radionuclide generator with ²²⁸Th as a parent radionuclide has been developed. The generator principle is based on diffusion of gaseous ²²⁰Rn emanating from strong anion exchange resin containing ²²⁸Th into a separate collector where post-decay ²¹²Pb is deposited on the collector walls. After a 48-hour operation cycle of the generator, sampling of ²¹²Pb in the form of solution in 0.1 M HCl is executed with approximately 40% yield of ²¹²Pb.
Another 212Pb generator design was also realized via ion exchange technique with 224Ra as parent source (T1/2 = 3,6 d). Actual implementation involves an ion exchange separation of 224Ra from 228Th with subsequent absorption of 224Ra in strong cation exchange column. ²¹²Pb could be then eluted with 1 M HCl.
The generators are supposed to be reloaded once in a few years because of long-lived parent 228Th (T1/2 = 1,9 y). The generators is developed for biological and radiochemical investigations in the field of obtaining radiopharmaceuticals for targeted therapy.
| The speaker is a student or young scientist | Yes |
|---|---|
| Section | 8. Nuclear technology and methods in medicine, radioecology |
